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本文介绍192例银屑病在不同类型、期别和皮损广泛程度时白细胞分类的变化,包括淋巴细胞形态和 ANAE 活性。白细胞总数和中性粒细胞在红皮病型和脓疱型中显著增高,各型患者均有淋巴细胞(特别是 T 细胞)缺陷。抗癌药物和免疫抑制剂能使原有 T 细胞缺陷加剧,这可能是导致本病易于复发且病情趋于顽固的原因。作者认为此类药物不宜作为治疗本病的首选药物,临床上应慎用。
This article describes the 192 cases of psoriasis in a wide range of different types, stages and lesions of leukocyte classification changes, including lymphocyte morphology and ANAE activity. The total number of leukocytes and neutrophils in the erythrodermic type and pustular type were significantly higher in all types of patients with lymphocytes (especially T cells) defects. Anti-cancer drugs and immunosuppressive agents can make the original T-cell defects worse, which may be the cause of this disease is easy to relapse and the disease tends to stubborn reason. The authors believe that such drugs should not be used as the drug of choice for the treatment of this disease, should be used with caution in clinical.