间充质干细胞是组织工程学和细胞治疗学中理想的种子细胞,可参与受损组织的修复。间充质干细胞除了可通过自身分化为受损组织的细胞直接参与修复外,还可通过旁分泌的形式,分泌一系列细胞因子,发挥抗炎抗凋亡、促新生血管生成、改善组织灌注等作用,促进受损组织的内源性修复,而且这种间接修复可能比直接修复更为重要。 Mesenchymal stem cells are ideal seed cells in tissue engineering and cell therapy and may participate in the repair of damaged tissues. Mesenchymal stem cells can participate in the repair through their own differentiation into damaged tissue cells, but also through the secretion of a series of cytokines in the form of paracrine, exert anti-inflammatory anti-apoptosis, angiogenesis, improve tissue perfusion Function to promote endogenous repair of damaged tissue, and this indirect repair may be more important than direct repair.