论文部分内容阅读
在工业卫生或职业病治疗药物筛选工作中,首先需要一种评价化学物质或药物毒性的简单方法,只有对该化学物质或药物的毒性有个初步了解,才能在予防中毒和药物治疗用量方面作到心中有数。本文就化学物质或药物毒性分级和衡量化学物质急性毒性的重要指标——半数致死量(LD_(50))测定的有关问题作一粗浅阐述,并介绍一种简易的LD_(50)计算法。
In the screening of pharmaceuticals for the treatment of industrial or occupational diseases, there is a need for a simple method of assessing the toxicity of a chemical substance or drug, and only a preliminary understanding of the toxicity of the chemical substance or drug can be made in terms of protection against poisoning and drug treatment There are a few hearts. In this paper, a brief introduction to the determination of LD50 (50), which is an important index to evaluate the toxicity of chemical substances or drugs and to measure the acute toxicity of chemical substances, is given. A simple LD 50 calculation method is introduced.