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应用准分子激光角膜原位磨镶术（Ｌａｓｉｋ）治疗高度近视５０例９１眼。术前屈光度为－８．００—－２５．０Ｄ（ｘ±ｓ：－１０．７３±４．４８Ｄ），其中散光度最高达－４．Ｄ。术后第１天，９１眼视力均有明显提高，１周后逐渐有下降趋势，３个月趋于稳定。术前屈光度≤－１２Ｄ的Ⅰ组，术后３个月屈光度为－０．２５±０．６５Ｄ，９７．９％的患眼术后裸眼视力达到术前矫正视力。术前屈光度＞－１２Ｄ的Ⅱ组，术后３个月屈光度－１．５９±２．２７Ｄ，７４．４％患眼术后裸眼视力达到术前矫正视力。存在的主要问题为术后屈光度欠矫，术后３个月Ⅰ组２０．８％欠矫，欠矫屈光度在－０．５—－２．０Ｄ，Ⅱ组３２．６％欠矫，欠矫屈光度在－１．０—－８．０Ｄ，（ｘ±Ｓ：－２．０９±１．８５Ｄ）。结论：准分子激光角膜原位磨镶术治疗高度近视早期效果令人满意。但如何减少术后屈光度回退，改进计算机切削程序，熟练手术技巧及Ｌａｓｉｋ术远期效果尚待更深入的研究。
Excimer laser in situ keratomileusis (Lasik) treatment of 50 cases of 91 cases of high myopia. Preoperative refraction was -8.00--25.0D (x ± s: -10.73 ± 4.48D), with astigmatism up to -4. D. On the first day after operation, visual acuity of 91 eyes increased significantly, gradually decreased after 1 week, and stabilized at 3 months. Group Ⅰ with preoperative refraction ≤ -12D had a refractive power of -0.25 ± 0.65D at 3 months postoperatively, and 97.9% of patients with uncorrected visual acuity achieved preoperative corrected visual acuity. Preoperative diopter> -12D in group Ⅱ, 3 months after refraction - 1.59 ± 2.27D, 74.4% of patients with uncorrected visual acuity reached preoperative corrected visual acuity. The main problem is postoperative refractive error due to surgery, 3 months after operation Ⅰ group 20.8% undercorrection, undercorrection diopter at -0.5--2.0D, Ⅱ group 32.6% undercorrection, undercorrection Diopter at -1.0--8.0D, (x ± S: -2.09 ± 1.85D). Conclusion: Excimer laser in situ keratomileusis is satisfactory in the early stage of high myopia. However, further studies on how to reduce postoperative refraction, improve computerized cutting procedures, skilled surgical techniques and the long-term effect of Lasik surgery are yet to be further studied.