生长抑素能选择性收缩内脏血管，减少肝脏血流，降低门脉压力，从而有效地控制食管静脉出血[1]。我院在1994年4月～1996年1月应用人工合成的生长抑素施他宁治疗食管静脉大出血12例，取得较好效果。现报道如下。1对象与方法对象：本组12例均为内镜确诊的食管静脉破裂大出血住院 Somatostatin can selectively shrink visceral blood vessels, reduce hepatic blood flow, reduce portal pressure, which effectively control the esophageal variceal bleeding [1]. Our hospital in April 1994 ~ January 1996 application of synthetic somatostatin somatostatin treatment of esophageal varices bleeding in 12 cases, and achieved good results. Report as follows now. 1 Subjects and Methods Subjects: The group of 12 patients were diagnosed endoscopic esophageal variceal bleeding in hospital