甲硝哒唑又名灭滴灵。是一种高效杀毛滴虫药物。用于治疗阴道毛滴虫感染,兰氏贾第鞭毛虫感染,此外对肠道及组织内阿米巴原虫也有杀灭作用。可用于治疗阿米巴痢疾和阿米巴肝脓肿。六十年代发现其具有良好的抗厌氧菌感染作用,但由于对厌氧菌的分离鉴定培养等技术比较复杂,所以甲硝哒唑的使用范围亦比较局限。随着对厌氧菌的分离等技术的提高,认识到厌氧菌已成为重要的病原。七十年代后期国外引起重视,对甲硝哒唑进行研究和临床应用。我国1985年版药典正式收载其为抗原虫和抗厌氧菌药物。并列为国家基本药物之一。由于它的毒性小,疗效高,应用范围广,所以临床使用 Metronidazole is also known as metronidazole. Is an efficient trichomonad drug. Trichomonas vaginalis for the treatment of Trichomonas vaginalis infection, Giardia lamblia infection, in addition to the intestinal and intramuscular amoeba also kill. Can be used to treat amoebic dysentery and amoebic liver abscess. In the 1960s, it was found to have good anti-anaerobic bacterial infection effects. However, due to the complexity of techniques such as isolation and identification of anaerobic bacteria, the metronidazole use range is also limited. With the separation of anaerobic bacteria and other technologies to improve, anaerobic bacteria have become recognized as an important pathogen. In the late seventies abroad, attention was paid to the study and clinical application of metronidazole. China’s 1985 edition of Pharmacopoeia formally contained its anti-protozoal and anti-anaerobic drugs. Side by side as one of the country’s basic drugs. Because of its toxicity, high efficacy, wide range of applications, so the clinical use