论文部分内容阅读
本文报告１９８７年１月～１９９０年１２月，作者应用顺铂、平阳霉素、长春新碱，术前诱导治疗口腔颌面部鳞癌６６例，其ＣＲ＋ＰＲ为７８．９％。顺铂剂量为４０ｍｇ／ｍ２、８０ｍｇ／ｍ２、１２０ｍｇ／ｍ２其缓解率为３７．５％、６０．０％、９０．６％，大剂量顺铂组优于其它剂量组（Ｐ＜０．０５）。化疗的主要毒副反应有消化道反应、骨髓抑制、脱发，而肾、肝、心和神经系统反应较轻。晚期口腔颌面部鳞癌术前诱导化疗以一疗程为宜。
This report from January 1987 to December 1990, the authors applied cisplatin, pingyangmycin, vincristine, preoperative induction of oral and maxillofacial squamous cell carcinoma of 66 cases, the CR + PR was 78.9%. The response rates of cisplatin 40mg / m2, 80mg / m2 and 120mg / m2 were 37.5%, 60.0% and 90.6% ). The main side effects of chemotherapy are gastrointestinal reactions, bone marrow suppression, hair loss, and kidney, liver, heart and nervous system reactions lighter. Advanced oral and maxillofacial squamous cell carcinoma preoperative chemotherapy to a course of treatment is appropriate.