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目的 :探讨在高原低氧条件下药物对人脑—体工作前后光觉的改善作用 ,为高原抗低氧药物的筛选、改善和提高脑—体功效能力积累借鉴资料 ;方法 :采用暗房夜光表检测法对服用三普红景天组、乙酰唑胺组和安慰剂组 ,每组 8人 ,于服药前进行运动前、运动后和睡眠剥夺前、睡眠剥夺 2 4h后和运动前、运动后的暗适应检测 ,服药 2 0天后 ,重复检测上述运动和睡眠剥夺 2 4h前后的暗适应时间 ,进行组间及服药前后的对比 ;结果 :红景天组、乙酰唑胺组服药后均较服药前暗适应时间显著缩短 (P <0 .0 1或P <0 .0 5 ) ,对照组服药前后无显著差异 (P >0 .0 5 ) ;红景天组与对照组 (服安慰剂 )服药后比较暗适应时间显著缩短 (P <0 .0 5 ) ;红景天组与乙酰唑胺组服药后比较无显著性差异 (P >0 .0 5 ) ;乙酰唑胺组与对照组比较服药后 ,暗适应时间虽缩短 ,但无统计学意义 (P <0 .0 5 ) ;结论 :红景天和乙酰唑胺均能有效的提高和改善低氧条件下脑—体工作前后的光觉功能 ,使缺氧状态下的暗适应时间缩短 ,但前者作用优于后者。
OBJECTIVE: To investigate the effect of the drug on the light perception before and after the human brain-body work under the condition of plateau hypoxia, to screen the anti-hypoxia drugs in the plateau and to improve and improve the brain-body efficacy. Methods: Test method for the use of Rhodiola Officinalis, acetazolamide group and placebo group, 8 in each group, before taking medication before exercise, after exercise and before sleep deprivation, sleep deprivation 24 h and before exercise, after exercise Dark adaptation test, 20 days after taking the test, repeat the above exercise and sleep deprivation 24 h before and after the dark adaptation time, before and after taking the comparison between the groups; Results: Rhodiola group, acetazolamide group after taking more medication (P <0.01 or P <0.05), there was no significant difference in the control group before and after taking the drug (P> 0.05); Rhodiola group and the control group (placebo) Compared with the control group, there was no significant difference between the Rhodiola group and the acetazolamide group (P> 0.05); the acetazolamide group and the control group After taking the medicine, the time of dark adaptation was shortened, but no statistical significance (P <0.05); On the other hand, both Rhodiola and acetazolamide can effectively improve and improve the photophysical function before and after brain-body work in hypoxia condition, shorten the time of dark adaptation in hypoxia condition, but the former is better than the latter.