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To explore the dynamic effects of exercise on IRS-2 protein content and tyrosine phosphorylation in DM rats,Sixty SD rats were divided into six groups: normal control group(NC)、diabetes mellitus group(DMC) and exercise group.The exercise groups exercised for different periods of time.The content and tyrosine phosphorylation of IRS-2 protein were measured by Western bolt analysis.Result showed that contents of IRS-2 protein in 60,120,180 min groups were enhanced up to 19.0%,22.4% and 17.2%(P<0.01) respectively,and the tyrosine phosphorylation of IRS-2 protein in 60,120,180 min group enhanced up to 43.1%,80.4% and 53%(P<0.01) respectively,compared with the DMC group.We concluded that that the contents and the tyrosine phosphorylation of IRS-2 protein had obvious time trait after exercise.
To explore the dynamic effects of exercise on IRS-2 protein content and tyrosine phosphorylation in DM rats, Sixty SD rats were divided into six groups: normal control group (NC), diabetes mellitus group (DMC) and exercise group. Exercise group exercised for different periods of time the content and tyrosine phosphorylation of IRS-2 protein were measured by Western bolt analysis. Result showed that contents of IRS-2 protein were 60 up to 120,180 min groups were up up to 19.0%, 22.4% and 17.2% (P <0.01) respectively, and the tyrosine phosphorylation of IRS-2 protein in 60,120,180 min group enhanced up to 43.1%, 80.4% and 53% (P <0.01) respectively, compared with the DMC group. We concluded that that the content and the tyrosine phosphorylation of IRS-2 protein had obvious time trait after exercise.