目的 :探讨侵及颅底的咽旁间隙肿瘤的手术进路及操作方法。方法 :对不同的进路进行比较 ,并对麻醉、操作、暴露肿瘤、防止并发症等进行探讨。结果 :1 0例良性肿瘤全部完整切除 ,无复发。在包膜内用手指进行分离可减少神经和血管损伤。结论 :口内进路可处理大部分良性肿瘤 ,但操作方法和进路的选择很重要。 Objective: To explore the surgical approach and operation method of parapharyngeal space tumor that invaded cranial base. Methods: To compare the different approaches, and to anesthesia, operation, exposure of the tumor, to prevent complications and so on. Results: All 10 cases of benign tumors were completely resected without recurrence. Finger separation in the capsule reduces nerve and vascular damage. Conclusion: The intraoral approach can handle most benign tumors, but the choice of method of operation and approach is important.