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目的观察养阴益气汤联合罗格列酮片对2型糖尿病胰岛素抵抗患者糖脂代谢的调节作用。方法选取医院收治的2型糖尿病患者98例,随机分为观察组和对照组,每组49例。对照组单纯服用罗格列酮片治疗,观察组给予养阴益气汤联合罗格列酮片治疗,均治疗4周,比较2组糖脂代谢水平变化和临床治疗效果。结果 2组治疗前糖代谢水平、脂代谢水平比较差异无统计学意义(P>0.05);观察组治疗后空腹血糖(FPG)、糖化血红蛋白(Hb A1c)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平均优于对照组(P<0.01)。观察组治疗总有效率为95.92%,高于对照组的75.51%(P<0.01)。结论 2型糖尿病患者采取养阴益气汤联合罗格列酮片治疗效果显著,可改善患者糖脂代谢水平,值得推广应用。
Objective To observe the regulatory effect of Yangyin Yiqi Decoction combined with rosiglitazone on glucose and lipid metabolism in type 2 diabetic patients with insulin resistance. Methods A total of 98 type 2 diabetic patients admitted to hospital were randomly divided into observation group and control group, with 49 cases in each group. The control group was treated with rosiglitazone alone. The observation group was given Yangyin Yiqi Decoction combined with rosiglitazone for 4 weeks. The changes of glucose and lipid metabolism and the clinical effect were compared between the two groups. Results There was no significant difference in the levels of glucose metabolism and lipid metabolism between the two groups before treatment (P> 0.05). The fasting blood glucose (FPG), Hb A1c, TC, triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) were significantly higher than those in the control group (P <0.01). The total effective rate of observation group was 95.92%, higher than 75.51% of control group (P <0.01). Conclusion Type 2 diabetes patients take yin yin qi decoction combined with rosiglitazone tablets significant effect, can improve the level of glucose and lipid metabolism in patients, it is worth promoting the application.