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目的探讨糖尿病(DM)合并脑梗死老年患者医院感染的高危因素和干预措施。方法回顾性分析720例DM合并脑梗死患者的临床资料,根据有无医院感染将患者分为感染组和非感染组;同时选取同期DM非脑梗死医院感染老年患者96例为对照组;比较各组参数异同。结果感染组患者年龄(71.68±8.93)岁、住院天数(31.08±11.21)d、空腹血糖(13.62±4.11)mmol/L、糖化血红蛋白A1C(14.85±5.08)、病程(5.03±4.19)d、侵入性操作、抗菌药物联合应用和免疫制剂及激素使用比例显著高于非感染组(P<0.05);感染组住院天数(31.08±11.21)d、侵入性操作比例显著高于对照组(P<0.05)。结论 DM合并脑梗死患者发生医院感染与年龄、住院天数、空腹血浆葡萄糖、糖化血红蛋白A1C、病程、侵入性操作、抗菌药联合和免疫制剂及激素应用有关;采取相应干预措施及控制危险因素可降低医院感染发生率。
Objective To investigate the risk factors and interventions of nosocomial infection in elderly patients with diabetes mellitus (DM) complicated with cerebral infarction. Methods The clinical data of 720 DM patients with cerebral infarction were retrospectively analyzed. According to the presence or absence of nosocomial infection, the patients were divided into infected group and non-infected group. At the same time, 96 elderly patients with DM non-cerebral infarction in the same period were selected as the control group. Group parameters similarities and differences. Results The patients in the infected group were 71.68 ± 8.93 years of age, 31.08 ± 11.21 days of hospitalization, 13.62 ± 4.11 mmol / L of fasting plasma glucose, 14.85 ± 5.08 of HbA1c and 5.03 ± 4.19 of course of disease (P <0.05). The number of days of hospitalization (31.08 ± 11.21) d and the rate of invasive operation in the infection group were significantly higher than those in the control group (P <0.05) ). Conclusions The nosocomial infection in patients with DM complicated with cerebral infarction is related to the age, hospitalization days, fasting plasma glucose, glycosylated hemoglobin A1C, duration of disease, invasive procedures, combination of antibacterial agents and immunologic agents and hormones. Corresponding interventions and risk factors can be reduced The incidence of nosocomial infection.