论文部分内容阅读
Survivin is a member of the inhibitor of apoptosis(lAP)protein family that interferes with post-mito- chondiral events including activation of caspases.To examine the regulation of survivin expression in re- sponse to radiation with different LET,we exposed human hepatoma hepG_2 cells to X-ray and C ions.The cellular sensitivities to radiation with high and low LET were determined by a colony forming assay.Sur- vivin mRNA was measured by rt-PCR,and survivin protein expression by Western blot analysis.We
Survivin is a member of the inhibitor of apoptosis (lAP) protein family that interferes with post-mito-chondiral events including activation of caspases. To examine the regulation of survivin expression in re- sponse to radiation with different LET, we exposed human hepatoma hepG_2 cells to X-ray and C ions. The cellular sensitivities to radiation with high and low LET were determined by a colony forming assay. Survival mRNA was measured by rt-PCR, and survivin protein expression by Western blot analysis. We