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目的探讨米索前列醇和米索前列醇协同缩宫素用于晚孕引产的临床效果。方法选取2015年1月—2016年1月因各种产科指征进行引产的单胎晚孕妊娠妇女40例,将其分为米索组(Ⅰ组)和协同组(Ⅱ组),每组20例。米索组(Ⅰ组)采用米索前列醇引产,协同组(Ⅱ组)采用米索前列醇协同缩宫素引产,观察两组取得的效果。结果协同组引产到临产时间明显短于米索组(P<0.05),两组引产成功率、新生儿出生情况相比差异性不大,且米索组有1例重复给药患者发生轻微的恶心,呕吐不适,无需处理。结论米索前列醇25ug阴道给药协同缩宫素2.5u加入5%葡萄糖注射液慢速静脉滴注用于晚期妊娠引产方便、安全,价格便宜,适用于基层医院,值得临床推广应用。
Objective To investigate the clinical effect of misoprostol and misoprostol in combination with oxytocin for induction of labor during late pregnancy. Methods From January 2015 to January 2016, 40 pregnant women with singleton pregnancy induced by various obstetric indications were divided into two groups: the misoprostol group (Ⅰ) and the synergistic group (group Ⅱ), and each group 20 cases. Misoprostol (group Ⅰ) was induced by misoprostol, and synergistic group (group Ⅱ) was treated with misoprostol in combination with oxytocin to observe the effects of the two groups. Results Compared with misoprostol (P <0.05), the time between induction and labor in the cooperative group was significantly shorter than that in the misoprostol group (P <0.05). There was no significant difference between the two groups in the success rate of induced labor and in the newborn’s birth rate. Nausea, vomiting, no need to deal with. Conclusion Misoprostol 25ug vaginal administration in combination with oxytocin 2.5u 5% glucose injection slow intravenous infusion for late pregnancy induction of labor is convenient, safe, inexpensive, suitable for primary hospitals, it is worthy of clinical promotion and application.