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目的探讨体外冲击波碎石(ESWL)联合坦索罗辛治疗输尿管下段结石的临床疗效。方法选择60例输尿管下段结石(大小约0.6～1.1 cm)患者,将患者随机分为对照组和观察组,每组30例,对照组采用ESWL治疗,观察组在对照组治疗的基础上加服坦索罗辛0.2 mg/d,每例患者观察4周,观察其临床疗效。结果治疗组排石率为86.7%(26/30),对照组为60.0%(18/30),平均排石时间:对照组为(8.9±3.1)d,观察组为(4.9±2.7)d,肾绞痛发生率:对照组为83.3%(25/30);观察组为53.3%(16/30),两组比较差异有统计学意义(P<0.05)。结论 ESWL联合坦索罗辛治疗输尿管下段结石安全、有效,可显著提高结石排除率,缩短排石时间,降低肾绞痛的发生率,值得临床推广使用。
Objective To investigate the clinical efficacy of extracorporeal shock wave lithotripsy (ESWL) combined with tamsulosin in the treatment of lower ureteral calculi. Methods Sixty patients with lower ureteral calculi (size 0.6 ~ 1.1 cm) were selected and randomly divided into control group and observation group, with 30 cases in each group. The control group was treated with ESWL. The observation group was served on the basis of the control group Tamsulosin 0.2 mg / d, each patient observed for 4 weeks to observe the clinical efficacy. Results In the treatment group, the rate of stone removal was 86.7% (26/30) in the control group and 60.0% (18/30) in the control group. The average time for stone discharging was (8.9 ± 3.1) days in the control group and (4.9 ± 2.7) days in the observation group , Incidence of renal colic: control group was 83.3% (25/30); observation group was 53.3% (16/30), the difference between the two groups was statistically significant (P <0.05). Conclusion ESWL combined with tamsulosin in the treatment of lower ureteral calculi is safe and effective, which can significantly improve the exclusion rate of stone, shorten the row of stone time and reduce the incidence of renal colic, which is worthy of clinical promotion.