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目的 探讨经皮支气管动脉灌注化疗和灌注化疗栓塞治疗中晚期肺癌的临床效果。资料与方法 对 5 7例肺癌患者施行了经皮支气管动脉灌注化疗或灌注化疗栓塞术。采用改良式Seldinger技术 ,行选择性和超选择性支气管动脉插管。经导管注入超液化碘油 (3～ 10ml)和吡柔比星 (10mg)的混悬液 ,然后注入另外 2种化疗药物 ,咳血患者最后用明胶海绵颗粒适量栓塞肿瘤周围小血管 ,支气管动脉主干保持通畅。结果 40例为富血管型(70 .18% ) ,17例 (2 9.82 % )为乏血管型。现存 15例中 ,半年生存率 10 0 % ,1年生存率 80 .0 0 %。死亡 33例 ,中位生存期 14.75个月 ,半年生存率 96 .97% ,1年生存率 73.33% ,2年生存率 33.81% ,3年生存率 9.0 9%。结论 经皮支气管动脉灌注化疗栓塞 ,三明治方法是治疗中晚期肺癌的最有效方法之一。可以确切延长中位生存期 ,提高患者生存质量。长期疗效需要大量随机增加病例及长期随访 ,不断提高肺癌介入治疗的临床效果
Objective To investigate the clinical effects of percutaneous bronchial artery infusion chemotherapy and chemoembolization in the treatment of advanced lung cancer. Materials and Methods Percutaneous bronchial artery infusion chemotherapy or chemoembolization was performed on 57 patients with lung cancer. Using modified Seldinger technique, line selective and superselective bronchial artery cannulation. Transcatheter injection of liquefied iodized oil (3 ~ 10ml) and pirarubicin (10mg) suspension, and then injected into the other two kinds of chemotherapy drugs, hemoptysis patients with gelatin sponge particles appropriate amount of embolization around the small blood vessels, bronchial artery Maintain unobstructed trunk. Results of 40 cases of vascular (70.18%), 17 cases (2 9.82%) of the lack of vascular type. The existing 15 cases, half a year survival rate of 10%, 1 year survival rate of 80 .0 0%. The median survival time was 14.75 months. The half-year survival rate was 96.97%, the one-year survival rate was 73.33%, the two-year survival rate was 33.81%, and the three-year survival rate was 9.09%. Conclusion Percutaneous bronchial arterial infusion of chemoembolization and sandwiches is one of the most effective methods for the treatment of advanced lung cancer. Can exactly extend the median survival and improve patient quality of life. Long-term efficacy requires a large number of randomly increased cases and long-term follow-up, and continuously improve the clinical effect of interventional treatment of lung cancer