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In this paper,we consider the following fractional Schr(o)dinger-Poisson problem:{ε2s(-△)su + V(x)u + φu =|u|p-1u,x ∈ RN,(-△)tφ =u2,x ∈ RN,where ε ＞ 0 is a small parameter,N≥ 3 and V(x) is a potential function.We construct non-radial sign-changing solutions,whose components may have spikes clustering at the local minimum point of V(x).