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目的观察老年心房颤动患者复律后小剂量胺碘酮口服维持窦性心律的有效性与安全性。方法将入选的70例老年心房颤动患者转复为窦性心律后随机分为实验组(n=32)和对照组(n=38),实验组口服胺碘酮,对照组口服普罗帕酮治疗。观察两组的疗效及不良反应发生率。结果实验治疗组维持窦性心律的效果明显优于对照组(P<0.05),且两组患者总的不良反应发生率差异无统计学意义(P>0.05)。结论小剂量胺碘酮(100 mg/d)在老年心房颤动患者复律后的窦性心律维持过程中的效果明显优于普罗帕酮,具有良好的有效性与安全性。
Objective To observe the effectiveness and safety of oral amiodarone in elderly patients with atrial fibrillation after oral administration of low-dose amiodarone to maintain sinus rhythm. Methods 70 elderly patients with atrial fibrillation were converted to sinus rhythm and then randomly divided into experimental group (n = 32) and control group (n = 38). The experimental group was treated with amiodarone and the control group received propafenone . The curative effect and incidence of adverse reactions in both groups were observed. Results The experimental treatment group was significantly better than the control group (P <0.05), and there was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusions Low dose amiodarone (100 mg / d) is superior to propafenone in the maintenance of sinus rhythm after cardioversion in elderly patients with atrial fibrillation. It has good efficacy and safety.