急性间质性肾炎（AIN）是以急性肾衰竭为重要临床表现，肾间质炎症细胞浸润为主的疾病，可发生于原有肾脏病变的基础上，是急性肾功能衰竭的主要原因。药物和感染是主要病因，除了流行性出血热和急性肾益肾炎，药物是主要因素，且有不断增多的趋势。引起急性间质性肾炎的主要药 Acute interstitial nephritis (AIN) is an important clinical manifestation of acute renal failure, interstitial inflammatory cell infiltration-based diseases that can occur in the original renal lesions on the basis of acute renal failure is the main reason. Drugs and infections are the major causes, with the exception of epidemic hemorrhagic fever and acute nephritic nephritis, where drugs are a major factor and there is a growing trend. Acute interstitial nephritis caused the main drug