论文部分内容阅读
目的 对 6例子宫内膜间质肉瘤进行临床病理分析 ,以探讨其诊断、鉴别诊断和治疗的方法。方法 对我院 1989～ 1999年收治 6例子宫内膜间质肉瘤进行回顾性分析 ,并随访其手术化疗治疗效果。病理资料重行常规切片 ,光镜观察 ,免疫组化染色。结果 6例子宫内膜间质肉瘤全部行手术治疗 ,术后辅以化疗等综合治疗 ,随访转移死亡 2例。采用S -P法行免疫组化染色 ,6例肿瘤细胞均表达Vimentin( +) ,Desmin( +)。结论 子宫内膜间质肉瘤较少见 ,好发于绝经前后妇女 ,不规则出血 ,迅速增大的腹块为主症 ,术前主要依靠B超检查诊断。病理组织学、免疫组化染色对子宫内膜间质肉瘤确诊、分型、鉴别诊断均有重要意义。手术切除辅以术后化疗仍是主要治疗方法。
Objective To analyze the clinicopathological features of 6 cases of endometrial stromal sarcoma in order to explore the methods of diagnosis, differential diagnosis and treatment. Methods A retrospective analysis was performed on 6 cases of endometrial stromal sarcoma treated in our hospital from 1989 to 1999, and the effect of surgical chemotherapy was followed up. Pathological data re-routine sections, light microscopy, immunohistochemical staining. Results All the 6 cases of endometrial stromal sarcoma were treated surgically and combined with chemotherapy after operation. Two cases died of follow-up and metastasis. Immunohistochemical staining was performed by S-P method. Vimentin (+) and Desmin (+) were all expressed in all 6 tumor cells. Conclusions Endometrial stromal sarcoma is rare, occurs in women before and after menopause, irregular bleeding, the rapid expansion of the main abdominal mass, preoperative mainly rely on B-ultrasound diagnosis. Histopathology, immunohistochemical staining for endometrial stromal sarcoma diagnosis, classification, differential diagnosis are of great significance. Surgical resection combined with postoperative chemotherapy is still the main treatment.