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目的 :探讨中晚期肝癌经导管注射抗癌药物或碘油和明胶海绵栓塞治疗后的疗效及影响预后的因素。方法 :接受介入治疗后有随访结果的中晚期肝癌患者 2 5例。 10例单纯经导管肝动脉注射抗癌药物为 A组 ;15例经肝动脉注射药物和碘油明胶海绵为 B组 ;对两组治疗后的疗效及影响预后的因素进行分析。结果 :1单因素分析显示有意义的预后因素是child分级 [1 ]、病灶类型、病灶大小、病灶数目、治疗后病灶大小改变及治疗次数 ;多因素分析显示 child分级、病灶大小、治疗方法及治疗次数是影响预后的主要因素。 2从治疗后肿块缩小及生存率来看 ,B组疗效明显优于 A组。结论 :中晚期肝癌放射介入治疗预后与患者一般情况、癌肿发展程度和治疗方法及时机有密切关系。对 child A级、肿瘤相对局限者 ,超过选择性肝动脉插管注射抗癌药物和碘油明胶海绵栓塞治疗 ,有助于延长患者生存的时间 ,提高生活质量 ,减轻医源性痛苦。
Objective : To investigate the efficacy of transcatheter infusion of anticancer drugs or lipiodol and gelatin sponge embolization in advanced and advanced hepatocellular carcinoma. Methods: Twenty-five patients with advanced liver cancer who had follow-up results after interventional treatment. 10 cases of pure transcatheter hepatic artery injection of anticancer drugs were group A; 15 cases of hepatic artery injection of drugs and lipiodol gelatin sponge were group B; the efficacy and prognostic factors of the two groups after treatment were analyzed. Results: 1 The univariate analysis showed that the significant prognostic factors were child classification [1 ], lesion type, lesion size, number of lesions, lesion size changes after treatment and number of treatments; multi-factor analysis showed that the child grading, lesion size, treatment methods and The number of treatments is the main factor that affects the prognosis. 2 From the perspective of tumor shrinkage and survival rate after treatment, the efficacy of group B was significantly better than that of group A. Conclusions: The prognosis of advanced interventional hepatocellular carcinoma (HCC) is closely related to the general condition of patients, the degree of cancer development and the method of treatment. For those with grade A and relatively limited tumors, the selective hepatic arterial infusion of anticancer drugs and lipiodol gelatin sponge embolization can help to prolong the survival time, improve the quality of life, and relieve the iatrogenic pain.