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内蒙古自治区中蒙医研究所将治疗风湿类风湿性关节炎的蒙药方剂”那鲁苏木珠尔”中的草乌和荜葜,分别提取出草乌总硷,荜葜挥发油,混合制成注射液称为那鲁注射液,(简称“那鲁”)。我们进行了镇痛抗炎作用的实验研究,并探讨了该注射液的有效成分和各成分间的相互影响。 草乌总硷小鼠皮下注射LD_(50)为0.32±0.045mg/Kg,与吕富华等氏测得的乌头硷LR_(50)0.295mg/Kg近似,荜葜挥发油与草乌总硷合用LD_(50)为0.83±0.027mg/Kg,
The Institute of Mongolian Medicine of Inner Mongolia Autonomous Region will extract the Aconitum arborescens and Radix Paeoniae Rubra from the Mongolian medicine prescription “Nalu Su Mujuer” for rheumatoid arthritis and extract the total components of Radix Aconiti Preparata and Radix Paeoniae Alba, respectively. Nalu injection, (“Nalu”). We conducted an experimental study of the analgesic and anti-inflammatory effects, and discussed the interaction between the active ingredients and the components of the injection. The total dose of LD_(50) for subcutaneous injection of Aconitum kusnezoffii was 0.32±0.045mg/Kg, which was similar to the LR_(50)0.295mg/Kg measured by Lvfuhua et al., and the combined use of LD_ and C. (50) is 0.83±0.027 mg/Kg,