论文部分内容阅读
目的：对１０１例恶性胶质瘤病人综合治疗效果进行评估。方法：病例分成三组，组Ⅰ（２６例）术后行同步放射ＡＣＮＵ化学治疗，随后每月重复１次化疗；组Ⅱ（３１例）手术后行同步放射ＶＭ２６、ＣＣＮＵ化学治疗，随后每月重复１次化疗；组Ⅲ（４４例）手术后单纯放射治疗作对照。结果：放射治疗后１月肿瘤体积缩小有效率分别为６５３８％、５４８４％、２０４５％。两组术后同步放射化学治疗与单纯放射治疗组对比有明显差异性，组Ⅰ与组Ⅲ１～２年生存率对比Ｐ＜００５，有差异性，组Ⅱ与组Ⅲ２年生存率对比Ｐ＜００５有差异性。结论：作者认为恶性胶质瘤术后同步放射化学治疗能缩小肿瘤体积，提高存活率。
Objective: To evaluate the comprehensive treatment effect of 101 patients with malignant glioma. METHODS: Cases were divided into three groups. Group I (26 cases) were treated with synchrotron ACNU chemotherapy and then chemotherapy was repeated once a month; Group II (31 cases) were treated with synchronous radiation VM26, CCNU chemotherapy followed by monthly The chemotherapy was repeated 1 times; Group III (44 cases) was treated with radiotherapy alone as a control. RESULTS: The tumor volume reduction effective rate was 65.8%, 54.4%, and 20.4%, respectively, after 1 month of radiotherapy. There was significant difference between the two groups in postoperative synchronous radiochemotherapy and radiotherapy alone. The 1-year to 2-year survival rates of group I and group III were P<005, with differences. The 2-year survival rates of group II and group III were compared. <005 is different. Conclusion: The authors believe that synchronous radiochemotherapy after glioma surgery can reduce tumor volume and improve survival.