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多发性骨髓瘤(multiple myeloma,MM)是浆细胞恶性增生性疾病,其特点为永生性的浆细胞产生单克隆免疫球蛋白(M蛋白)并表现为复杂的细胞遗传学和分子遗传学特征,本文就MM中聚糖分子改变的研究进展做一综述。
Multiple myeloma (MM) is a plasma cell malignant proliferative disease characterized by immortal plasma cells producing monoclonal immunoglobulin (M protein) and exhibiting complex cytogenetic and molecular genetic features, This article reviews the progress in the molecular changes of glycan in MM.