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目的对影响耐药结核病患者形成的原因及对策进行分析。方法选取2012年6月至2015年10月在伊犁州新华医院肺科进行治疗的肺结核患者200例,依据耐药情况给予分组,常规组100例,为治疗中没有耐药情况患者;耐药组100例,为诊疗中发生耐药情况,对两组患者的治疗情况进行分析。结果常规组应用抗生素使用数量、不规范治疗、药物反应被动停药、经济条件、不良嗜好、病程时间、年龄、治疗依从性均显著优越于耐药组患者,差异性显著,存在统计学意义(P<0.05)。针对于耐药组患者给予健康教育管理,耐药组患者的痰液检查情况、疾病知识掌握明显改善,与治疗前对比,存在显著差异性,具有统计学意义(P<0.05)。结论影响耐药结核病患者形成的原因主要抗生素使用数量、不规范治疗、药物反应被动停药、经济条件、不良嗜好、治疗依从性等,对于耐药肺结核患者给予健康教育管理,增加患者的临床治疗知识,明显增加患者对于疾病知识的掌握,同时明显改善患者的耐药情况,因此对于存在上述因素患者应增加健康教育管理,减少耐药的发生和发展,提高患者的生活质量。
Objective To analyze the causes of formation of drug-resistant TB patients and the countermeasures. Methods From June 2012 to October 2015, 200 patients with pulmonary tuberculosis who were treated in Xinhua Hospital of Pulley Hospital of Ili District were enrolled in this study. The patients were divided into three groups according to drug resistance. The patients in conventional group were treated with no drug resistance. 100 cases, for the emergence of drug resistance in the treatment, the treatment of two groups of patients were analyzed. Results In the conventional group, the number of antibiotics used, non-standard treatment, passive withdrawal of drug reactions, economic conditions, bad habits, duration of disease, age, treatment compliance were significantly superior to the drug-resistant patients, the difference was statistically significant P <0.05). For the patients in the drug-resistant group, health education management, sputum examination in the drug-resistant group, and disease knowledge mastery were significantly improved. There was significant difference compared with before treatment, with statistical significance (P <0.05). Conclusions The main causes of the formation of drug-resistant TB patients are the use of antibiotics, non-standard treatment, passive withdrawal of drug reactions, economic conditions, bad habits and treatment compliance, and give health education management to patients with drug-resistant pulmonary tuberculosis and increase the clinical treatment of patients Knowledge, significantly increase the patient’s grasp of disease knowledge, and significantly improve the patient’s drug resistance, so for the presence of these factors should increase health education and management, reduce the occurrence and development of drug resistance, improve patient quality of life.