我科自1986年1月～1989年10月收治新生儿硬肿症130例,死亡37例(28.48％)。其中有出血性并发症者34例,死亡22例(70.59％)占本组总死亡数的59.46％(22/37)。34例中男20例,女14例。生后3天内入院者19例、～7天13例、>7天2例;早产儿24例,足月儿10例。出生体重<2500g者27例,>2500g7例。中度硬肿症15例,重度19例。发病因素中,新生儿窒息13例,重症感染23 Our department from January 1986 ~ October 1989 admitted to 130 cases of neonatal sclera, 37 patients died (28.48%). Among them, there were 34 cases of hemorrhagic complications, 22 cases (70.59%) died of this group accounted for 59.46% (22/37) of the total number of deaths. 34 cases of 20 males and 14 females. 19 cases were admitted within 3 days after birth, 13 cases were ~ 7 days, 2 cases> 7 days, 24 cases were preterm and 10 cases were full-term. Birth weight <2500g in 27 cases,> 2500g7 cases. Moderate sclerosis in 15 cases, severe in 19 cases. Among the risk factors, 13 were neonatal asphyxia and 23 were severe infections