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目的:研究锐器伤梅毒职业暴露的预防处理,为医务工作者提供更好的梅毒暴露安全防护措施和帮助。方法:将87例锐器伤梅毒职业暴露者随机分为两组。使用苄星青霉素治疗的为治疗组(42例),该组局部未经及时正规处理,48小时内给苄星青霉素120万U单次肌注;局部处理的为对照组(47例),立即近心端挤压,再用肥皂或医用洗手液和流动水进行冲洗,再用0.5%碘伏消毒包扎伤口。于0、1、2、3、6个月观察两组梅毒血清学变化。结果:治疗组与对照组均无感染。结论:锐器伤梅毒职业暴露后立即给予挤压清洗消毒伤口就可以起到预防作用。如手术不能停止等情况可进行药物预防处理。
Objective: To study the prevention and treatment of occupational exposure to sharp syphilis and to provide health care workers with better syphilis exposure safety protection and assistance. Methods: 87 cases of sharp occupational syphilis occupational exposure were randomly divided into two groups. For the treatment group (n = 42) treated with penicillin, the group was given a single intramuscular injection of penicillin 1.2 million U intramuscularly within 48 hours without treatment, and the control group (n = 47) Near the end of the squeeze, and then wash with soap or medical hand sanitizer and running water, then 0.5% iodophor disinfection dressing wounds. Serum changes of syphilis in two groups were observed at 0, 1, 2, 3 and 6 months. Results: The treatment group and the control group were not infected. CONCLUSIONS: The sharp wounds syphilis given immediately after occupational exposure to squeeze cleaning and disinfection wounds can play a preventive role. Such as surgery can not stop the situation can be drug prevention treatment.