肝内胆汁郁积性黄疸可由多种病因引起,常见者为甲型或乙型肝炎病毒、急性炎症感染和药物(甲基睾丸酮、氯丙嗪、保泰松和卡巴砷)等。肝内胆汁郁积性黄疸的病程较长,治疗颇为棘手。本文报道5例肝内胆汁郁积性黄疸,其中4例经剖腹探查或肝组织学检查证实。经苯巴比妥治疗后,黄疸明显减退或消失,血清胆红素亦显著下降或恢复正常,皮肤瘙痒消失。在疗程中未发现明显付作用,全身情况逐日好转。病例摘要例1 男性,38岁,工人。因进行性黄疸伴全身皮肤 Intrahepatic cholestasis jaundice can be caused by a variety of causes, common for hepatitis A or B, acute inflammatory infections and drugs (methyl testosterone, chlorpromazine, phenylbutazone and carboplatin arsenic) and so on. Intrahepatic cholestasis of jaundice longer course of treatment is quite difficult. This article reports 5 cases of intrahepatic cholestatic jaundice, of which 4 cases were confirmed by laparotomy or liver histology. After phenobarbital treatment, jaundice significantly decreased or disappeared, serum bilirubin also significantly decreased or returned to normal, the skin itching disappeared. In the course of treatment did not find significant pay role, the general condition improved day by day. Case Summary 1 male, 38 years old, worker. Due to progressive jaundice with whole body skin