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目的:了解长沙市美沙酮门诊患者服药依从性现状及主要影响因素,分析各因素对其服药依从性的综合影响。方法:分层抽样的方法使用修订问卷调查长沙市3个美沙酮门诊共734名毒品成瘾者。相关性分析的方法了解12个因素对门诊患者服药依从性的影响,因子分析的方法筛选出若干主成分,回归分析的方法对各主成分进行线性拟合,分析各主成分对门诊患者服药依从性的综合影响。结果:影响美沙酮患者服药依从性的12个因素可以归纳为5个主成分:服药环境和疗效(贡献率32.150%)、心理状态(贡献率21.005%)、社会和朋友支持(贡献率10.686%)、家人关怀(贡献率9.181%)、其他(贡献率7.976%)。5个主成分所拟合的多元线性回归方程有统计学意义(F=43.82,P=0.00),相关系数R=0.81,决定系数R2=0.66。结论:影响长沙市美沙酮门诊患者服药依从性的主要原因是:服药环境和疗效不佳、心理状态失衡、社会和朋友支持缺失、家人关怀不强。
OBJECTIVE: To understand the status of drug compliance and the main influential factors in methadone outpatient service in Changsha and to analyze the comprehensive impact of various factors on its adherence to medication. Methods: Stratified Sampling Method A total of 734 drug addicts from 3 methadone clinics in Changsha were surveyed using a revised questionnaire. Correlation analysis method to understand the influence of 12 factors on outpatient medication compliance, the method of factor analysis selected a number of principal components, regression analysis of the principal components of a linear fit, analysis of the principal components of outpatients medication compliance The combined effect of sex. Results: The 12 factors influencing medication adherence of methadone patients can be summarized into five main components: medication environment and efficacy (contribution rate 32.150%), psychological status (contribution rate 21.005%), social and friend support (contribution rate 10.686%) , Family care (contribution rate 9.181%), others (contribution rate 7.976%). The multivariate linear regression equation fitted by five principal components was statistically significant (F = 43.82, P = 0.00), the correlation coefficient R = 0.81, and the determination coefficient R2 = 0.66. Conclusion: The main reasons influencing medication adherence in methadone outpatient service in Changsha are as follows: poor medication environment and curative effect, unbalanced psychological status, lack of social and friends support, lack of family care.