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目的:观察清热益肾方结合柳氮磺胺吡啶治疗强直性脊柱炎的效果。方法:选择2015年7月-2016年8月来我院治疗强直性脊柱炎的患者92例作为研究对象,采用随机信封法将其分为对照组(n=46)与实验组(n=46),对照组给予柳氮磺胺吡啶治疗,实验组给予清热益肾方结合柳氮磺胺吡啶治疗,对比分析两组患者临床症状与体征积分情况、实验室指标。结果:实验组临床症状及体征积分情况、实验室指标明显低于对照组,P<0.05。结论:在强直性脊柱炎临床治疗中,采用清热益肾方结合柳氮磺胺吡啶治疗,既可改善临床症状与体征,又可降低实验室指标,值得临床推广应用。
Objective: To observe the effect of Qingre Yishen Decoction combined with sulfasalazine on ankylosing spondylitis. Methods: A total of 92 patients with ankylosing spondylitis in our hospital from July 2015 to August 2016 were enrolled in this study. They were randomly divided into control group (n = 46) and experimental group (n = 46) ). The control group was treated with sulfasalazine. The experimental group was given Qingre Yishen combined with sulfasalazine, and the clinical symptoms and signs scores and laboratory indexes of the two groups were compared. Results: The clinical symptoms and signs of the experimental group, laboratory indicators were significantly lower than the control group, P <0.05. Conclusion: In the clinical treatment of ankylosing spondylitis, the treatment of Qingre Yishen combined with sulfasalazine can not only improve the clinical symptoms and signs, but also reduce the laboratory index, which is worthy of clinical application.