萘可引起实验动物的溶血性贫血、白内障并可致小鼠肺损伤。其毒效应与萘形成高活性醌有关。已证明醌能造成还原型谷胱甘肽(GSH)消耗而引起组织过氧化作用的增强。萘还可损伤谷胱甘肽过氧化物酶(GSH-Px)系统。作者证实即使GSH水平增高超过对照组,但当含硒酶GSH-Px受损时,活体实验也会发生心脏组织过氧化。因此萘的毒性是由组织过氧化增加,还是由萘引起GSH-Px减少所致尚须加以研究。已证实给与萘结构相似的卤代 Naphthalene can cause hemolytic anemia in experimental animals, cataracts and can cause lung injury in mice. Its toxic effects and naphthalene formation of high activity quinone. Quinone has been shown to cause reduced glutathione (GSH) depletion resulting in increased tissue peroxidation. Naphthalene can also damage the glutathione peroxidase (GSH-Px) system. The authors confirm that cardiac tissue peroxidation occurs in vivo even when the GSH-Px selenium is impaired, even though GSH levels increase more than in the control group. Therefore, the toxicity of naphthalene increased tissue peroxidation, or caused by naphthalene reduced GSH-Px still need to be studied. Halo groups similar to naphthalene have been demonstrated