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依诺沙星具有抗菌谱广、杀菌力强、疗效高、毒性低、使用安全等优点。现广泛用于泌尿系、呼吸道、消化道、妇科、外科、皮肤软组织及耳鼻喉科等感染,我们用其与甲硝唑、地塞米松等制成复方依诺沙星滴耳液,用于治疗急、慢性化脓性中耳炎、外耳道炎、鼓膜炎等,依诺沙星和甲硝唑的含量测定已多有报道,我们对此滴耳液中的依诺沙星和甲硝唑同时用高效液相法测定含量,现报告如下: 一、仪器与试药 SP1000高效液相泵,UV2000紫外—可见检测器及SP4600电脑积分仪(美国光谱物理公司)。甲
Enoxacin has broad antimicrobial spectrum, bactericidal power, high efficacy, low toxicity, the use of safety and so on. Now widely used in urinary tract, respiratory tract, gastrointestinal, gynecology, surgery, skin and soft tissue and otolaryngology and other infections, we use it with metronidazole, dexamethasone and other compound enoxacin ear drops for The treatment of acute and chronic suppurative otitis media, otitis externa, tympanitis, enoxacin and metronidazole determination has been reported, we have this ear drops of enoxacin and metronidazole with high efficiency Liquid phase determination of the content, are reported as follows: First, instruments and reagents SP1000 high-performance liquid pump, UV2000 UV - Vis detector and SP4600 computer integrator (the United States spectral physics company). A