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目的探讨~(18)F-FDG SPECT符合线路显像对诊断颈部淋巴结转移癌的预测价值。方法收集2015年11月—2016年5月浙江衢化医院就诊的46例疑似颈部淋巴结转移癌患者临床病理资料,所有入组患者分别行~(18)FFDG SPECT符合线路显像和常规影像学的检查,入组患者均取得病理结果,比较不同检查方法在颈部淋巴结转移癌诊断中的灵敏度、特异度、准确率、阳性预测值及阴性预测值;测定入组患者病灶与正常组织的放射线基线比值(T/N比值),采用独立样本t检验分析淋巴结转移癌患者~(18)F-FDG SPECT符合线路显像的显像特点,比较不同检查方法在其他转移灶诊断中的价值。结果~(18)F-FDG SPECT符合线路显像和常规影像学检查对颈部淋巴结转移癌患者的原发灶诊断灵敏度、特异度、准确率、阳性预测值及阴性预测值分别为87.5%、83.3%、87.0%、97.2%、50.0%和70.0%、33.3%、65.2%、87.5%、14.3%;淋巴结转移癌患者病灶T/N平均值为7.15±3.51,非淋巴结转移癌患者病灶T/N平均值为4.26±2.37,明显低于淋巴结转移癌患者,差异有统计学意义(P<0.05);~(18)F-FDG SPECT符合线路显像共检出转移淋巴结和其他转移灶平均数分别为10.24±3.47和1.58±1.64,常规影像学检查检出平均数分别为6.18±4.38和0.62±0.48,明显低于~(18)F-FDG SPECT符合线路显像,差异均有统计学意义(P<0.05)。结论~(18)F-FDG SPECT符合线路显像对颈部淋巴结转移癌诊断及预测价值更高,同时还可更高效的发现其他转移灶。
Objective To investigate the predictive value of ~ (18) F-FDG SPECT coincidence imaging in the diagnosis of cervical lymph node metastases. Methods The clinical data of 46 patients with suspected cervical lymph node metastasis from September 2015 to May 2016 in Zhejiang Quhua Hospital were collected. All the patients were enrolled in this study. The patients underwent 18 FFDG SPECT coincidence imaging and conventional imaging Of the patients in the study group were pathologically confirmed. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of different examinations in the diagnosis of cervical lymph node metastasis were compared. The radiores of lesion and normal tissue in the patients were determined (T / N ratio). The imaging characteristics of ~ (18) F-FDG SPECT line imaging in patients with lymph node metastatic cancer were analyzed by independent sample t-test. The diagnostic value of different examination methods in other metastases was compared. Results The diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive value of ~ (18) F-FDG SPECT coincidence imaging and routine radiological imaging in patients with cervical lymph node metastasis were 87.5% 83.3%, 87.0%, 97.2%, 50.0% and 70.0%, 33.3%, 65.2%, 87.5% and 14.3%, respectively. The mean T / N of lesions in patients with lymph node metastasis was 7.15 ± 3.51, N average was 4.26 ± 2.37, which was significantly lower than that in patients with lymph node metastasis (P <0.05). The average number of metastatic lymph nodes and other metastases was detected by ~ (18) F-FDG SPECT coincidence imaging Respectively 10.24 ± 3.47 and 1.58 ± 1.64, the average number of routine imaging examination were 6.18 ± 4.38 and 0.62 ± 0.48, respectively, which was significantly lower than that of 18 F-FDG SPECT line imaging, the differences were statistically significant (P <0.05). Conclusions ~ (18) F-FDG SPECT line imaging is more valuable for the diagnosis and prognosis of cervical lymph node metastases, and more efficient detection of other metastases.