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真菌性角膜溃疡的治疗一直是个难点。近些年来,随着抗真菌药如氟康唑的出现,治疗上出现了转机。现将我院1998年10月至2001年1月收治的15例用氟康唑治疗的效果报告如下。 1 临床资料本组15例中男8例,女7例,年龄35～62岁。按以下标准诊断:①植物外伤史;②长期抗生素及皮质激素治疗无效;③典型眼部症状:溃疡呈灰白色,质硬,表面粗糙,后弹力层皱摺,房闪阳性;④角膜刮片用氢氧化钾湿片法查菌丝为阳性。有的病例不典型,但只要发现菌丝即可确诊。 2 治疗方法和结果确诊后即予0.2%氟康唑结膜下注射0.3ml 1/d,0.2%氟康唑点患眼15min一次;病灶好转后改为点患眼6/d,结膜下注射2/周,并加用氧氟沙星眼液点患眼4/d,
The treatment of fungal corneal ulcers has been a difficult point. In recent years, with the emergence of anti-fungal drugs such as fluconazole, treatment has turned a corner. Now in our hospital from October 1998 to January 2001 admitted 15 cases of fluconazole treatment effect reported below. 1 Clinical data The group of 15 patients, 8 males and 7 females, aged 35 to 62 years. According to the following criteria diagnosis: ① history of plant trauma; ② long-term antibiotics and corticosteroid therapy is invalid; ③ typical ocular symptoms: gray ulcers, hard, rough surface, wrinkled after the elastic layer, atrial flickering; ④ corneal scraping Potassium hydroxide wet test method for mycelial positive. Some cases are not typical, but as long as mycelium can be confirmed. 2 treatment methods and results were confirmed 0.2% fluconazole subconjunctival injection of 0.3ml 1 / d, 0.2% fluconazole point of the eye for 15min once; lesions improved to the point of eye 6 / d, subconjunctival injection 2 / Week, plus ofloxacin eye drops eye 4 / d,