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目的分析精准腹腔镜Roux-en-Y胃旁通路治疗肥胖性2型糖尿病的临床疗效。方法选取8例肥胖性2型糖尿病患者的临床资料进行回顾性分析,所有患者均行精准腹腔镜Roux-en-Y胃旁路术治疗,对比治疗前与治疗后各项指标的变化。结果治疗后体质量指数明显低于治疗前,差异有统计学意义(P<0.05);治疗后空腹时的血糖、胰岛素、糖化血红蛋白水平、C肽均明显低于治疗前,差异有统计学意义(P<0.05);治疗后餐后2 h血糖明显低于治疗前,餐后2 h胰岛素、餐后2 h C肽均明显高于治疗前,差异有统计学意义(P<0.05)。结论精准腹腔镜Roux-en-Y胃旁通路治疗肥胖性2型糖尿病的临床疗效显著,符合胃肠道生理,值得在临床上推广与应用。
Objective To analyze the clinical efficacy of precise laparoscopic Roux-en-Y gastric bypass in the treatment of obese type 2 diabetes mellitus. Methods The clinical data of 8 patients with obese type 2 diabetes mellitus were retrospectively analyzed. All the patients underwent laparoscopic Roux-en-Y gastric bypass surgery. The changes of the indexes before and after treatment were compared. Results After treatment, the body mass index was significantly lower than before treatment, the difference was statistically significant (P <0.05); fasting blood glucose, insulin, HbA1c, C-peptide were significantly lower after treatment than before treatment, the difference was statistically significant (P <0.05). The postprandial blood glucose at 2 h after treatment was significantly lower than that before treatment, 2 h postprandial insulin and 2 h postprandial C peptide were significantly higher than those before treatment (P <0.05). Conclusion The precise laparoscopic Roux-en-Y gastric bypass for the treatment of obese type 2 diabetes has a significant clinical effect and is in line with gastrointestinal physiology. It is worth to be popularized and applied clinically.