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程序心室刺激可用于指导持续性室性心动过速患者选择有效的抗心律失常药物,但多种药物的反复试验,既昂贵又费时,而且患者亦难于接受。为此,本文研究是否能以普鲁卡因酰胺在电生理研究中的效应来预测其它常用药物的效应。方法:126名受试者,绝大多数患有动脉粥样硬化性心脏病。电生理研究系经皮下将四极导管插至右心室,远端一对电极作为发放刺激用,近端一对电极作记录用,另插入一根三极导管记录希氏束电图。由程序刺激器发放矩形脉冲波,脉冲时限为1毫
Procedural ventricular stimulation can be used to guide the selection of effective antiarrhythmic drugs in patients with persistent ventricular tachycardia, but repeated trials of multiple drugs are both expensive and time-consuming and difficult for patients to accept. For this reason, we investigated whether the effects of other commonly used drugs could be predicted by the effect of procainamide in electrophysiological studies. Methods: 126 subjects, the vast majority with atherosclerotic heart disease. Electrophysiology Department of subcutaneous four-electrode catheter inserted into the right ventricle, a pair of distal electrodes as a release stimulus, a pair of proximal electrodes for recording, and the other into a three-pole catheter recording His bundle. Issued by the program stimulator rectangular pulse, pulse time limit of 1 millisecond