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本文对43例卵巢癌病人进行顺铂(DDP)术前、术中、术后20~40mg腹腔内化疗,其中19例行根治术,24例行减灭术。腹腔内化疗平均4~6疗程,DDP总量平均580mg。手术前后30例腹水得到控制,部分病人为手术创造了条件。Ⅰc期4例,1例生存3年,3例生存5年。Ⅱa期5例,Ⅱb期8例生存24~40个月。Ⅲ期22例生存12~24个月。Ⅳ期4例生存3~6个月。小剂量DDP腹腔内化疗不须水化,化疗反应轻,使用方便,效果良好。
In this paper, 43 cases of ovarian cancer patients underwent cisplatin (DDP) preoperative, intraoperative and postoperative 20 ~ 40mg intraperitoneal chemotherapy, of which 19 cases of radical mastectomy, 24 cases of surgical resection. Intraperitoneal chemotherapy an average of 4 to 6 courses, the average total DDP 580mg. 30 cases of ascites before and after surgery to be controlled, some patients to create the conditions for surgery. Ⅰc 4 cases, 1 case survived 3 years, 3 cases survived 5 years. 5 cases of stage IIa, 8 cases of stage IIb survived for 24 to 40 months. Twenty-three patients survived for 12 to 24 months. 4 cases of 4 survived 3 to 6 months. Low-dose DDP intraperitoneal chemotherapy without hydration, chemotherapy response light, easy to use, the effect is good.