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慢性特发性血小板减少性紫癜(ITP)是一种自身免疫性疾病,治疗用皮质类固醇、其他免疫抑制药物或脾切除术。皮质类固醇有一些众所周知的重要副作用和耐受性差,在许多病例有暂时性功效。其他细胞毒药物的功效和作用尚未确定,况且对年青病人要考虑到长期应用可影响生育力和促进肿瘤形成的可能。因此,许多慢性ITP病人适应于脾切除,但脾切除不是在所有病例都能导致缓解,且能发生晚期并发
Chronic idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease that is treated with corticosteroids, other immunosuppressive drugs, or splenectomy. Corticosteroids have some of the well-known important side effects and poor tolerance, with transient effects in many cases. The efficacy and role of other cytotoxic drugs have not yet been established, and young patients are warranted to consider that long-term use can affect fertility and promote tumor formation. Therefore, many chronic ITP patients are adapted to splenectomy, but not all cases of splenectomy can lead to remission, and can occur late concurrency