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目的探讨2型糖尿病患者左室舒张功能减退相关临床影响因素。方法超声心动图检查2013年1月-2013年8月住院的724例2型糖尿病患者。结果 (1)2型糖尿病患者合并左室舒张功能减退的发生率为73.8%;在年龄、Hb A1c、糖尿病病程、BMI、高血压、高脂血症、糖尿病微血管并发症、糖尿病大血管并发症方面,糖尿病合并左室舒张功能减退组与无左室舒张功能减退组患者之间差异均有统计学意义(χ2=13.416、10.227、12.218、4.42、21.823、10.974、7.838、26.145,P=0.000、0.001、0.000、0.000、0.035、0.005、0.000);(2)2型糖尿病患者的年龄、BMI和Hb A1c与左室舒张功能减退有显著相关性(OR=1.175、1.248、1.383,P=0.000、0.017、0.029)。结论2型糖尿病患者合并左室舒张功能减退相当常见,糖尿病年龄、BMI和Hb A1c是影响左室舒张功能减退发生的独立危险因素。
Objective To investigate the clinical influencing factors of left ventricular diastolic dysfunction in type 2 diabetic patients. Methods Echocardiography was performed on 724 type 2 diabetic patients hospitalized from January 2013 to August 2013. Results (1) The incidence of left ventricular diastolic dysfunction was 73.8% in patients with type 2 diabetes mellitus (T2DM). There was no significant difference in age, Hb A1c, duration of diabetes, BMI, hypertension, hyperlipidemia, diabetic microvascular complications, There was significant difference between diabetic patients with left ventricular diastolic dysfunction and those with no left ventricular diastolic dysfunction (χ2 = 13.416,10.227,12.218,4.42,21.823,10.974,7.838,26.145, P = 0.000, 0.001, 0.000, 0.000, 0.035, 0.005, 0.000); (2) There was a significant correlation between age, BMI and Hb A1c in patients with type 2 diabetes and left ventricular diastolic dysfunction (OR = 1.175,1.248,1.383, P = 0.000, 0.017, 0.029). Conclusions Patients with type 2 diabetes mellitus with left ventricular diastolic dysfunction are quite common. Age of diabetes, BMI and Hb A1c are independent risk factors affecting left ventricular diastolic dysfunction.