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目的探讨对高脂血症患者实施阿托伐他汀片不同给药时间治疗的方法和临床效果。方法 90例高脂血症患者,随机分成A、B、C组,各30例。A组患者实施早餐前2 h服药阿托伐他汀片治疗,B组患者早餐后2 h服药阿托伐他汀片治疗,C组患者晚餐后2 h服药阿托伐他汀片治疗,观察三组患者的治疗效果。结果 C组治疗总有效率为96.67%显著高于B组的80.00%,B组治疗总有效率高于A组的53.33%,差异均具有统计学意义(P<0.05)。C组血脂改善情况显著优于B组,B组血脂改善情况优于A组,差异均具有统计学意义(P<0.05)。结论高脂血症患者实施晚餐后2 h口服阿托伐他汀片治疗的疗效显著,降脂效果好,值得临床进行推广。
Objective To investigate the method and clinical effect of atorvastatin tablets on the administration of different time in patients with hyperlipidemia. Methods 90 cases of hyperlipidemia patients were randomly divided into A, B, C group, 30 cases each. Patients in group A were treated with atorvastatin 2 h before breakfast, patients in group B were treated with atorvastatin 2 h after breakfast, patients in group C were treated with atorvastatin 2 h after dinner, Therapeutic effect. Results The total effective rate of C group was 96.67%, which was significantly higher than that of B group (80.00%). The total effective rate of B group was higher than that of A group (53.33%). The difference was statistically significant (P <0.05). The improvement of blood lipids in group C was significantly better than that in group B. The improvement of blood lipids in group B was better than that in group A, the differences were statistically significant (P <0.05). Conclusion Hyperlipidemia in patients with dinner 2h after oral atorvastatin tablets treatment of significant effect, lipid-lowering effect, it is worth promoting the clinical.