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目的:探讨氨酚羟考酮片纳肛治疗中重度癌性疼痛。方法:对46例不能口服药物的中重度癌痛患者,以氨酚羟考酮片纳肛治疗,观察疗效及不良反应。结果:氨酚羟考酮片纳肛后2 h的VAS评分结果显示中重度癌痛患者缓解显效率为65.2%,有效率为91.3%,用药前后比较有显著差异(P<0.01)。氨酚羟考酮片纳肛不良反应有头晕2例(4.3%),恶心1例(2.2%),嗜睡1例(2.2%),无需治疗,均能自行好转。结论:氨酚羟考酮片纳肛可用于不能口服药物的中重度癌痛患者,尤其是中度癌痛患者,不良反应较少。
Objective: To investigate the treatment of moderate to severe carcinomatous pain with oxycodone tablets. Methods: Forty-six patients with moderate-to-severe cancer pain who could not be orally administered were treated with paracetamol and oxycodone tablets. Analgesia and adverse reactions were observed. Results: The VAS score of oxycodone analgesia 2 hours after anal appearing showed that the effective rate of relieving was 65.2% and the effective rate was 91.3%. There was significant difference before and after treatment (P <0.01). There were 2 cases (4.3%) of nausea, 1 case of nausea (2.2%) and 1 case of drowsiness (2.2%), which could be improved without treatment. Conclusion: Analgesic oxycodone tablets anal anal can be used in patients with moderate to severe cancer pain can not be orally administered, especially in patients with moderate cancer pain, with fewer adverse reactions.