论文部分内容阅读
目的初步探讨~(125)I粒子植入治疗颈部淋巴结转移癌的疗效及对患侧臂丛神经损伤的影响。方法回顾性分析接受~(125)I粒子植入治疗的22例颈部淋巴结转移癌患者共26个病灶。评价患者临床受益反应、2个月局部控制率、1年生存率及并发症情况。结果随访时间2~21个月,中位时间11个月,临床受益率72.7%,有效率61.5%,2个月局部控制率84.6%,1年生存率36.4%。其中4例患者出现臂丛神经受损。结论 CT引导下~(125)I粒子植入低剂量长时间持续内照射治疗颈部淋巴结转移癌的近期疗效较好,创伤小;但引起臂丛神经损伤是不可治愈的并发症之一,造成患者残疾,严重影响患者的生活质量。
Objective To investigate the efficacy of ~ (125) I seed implantation in the treatment of cervical lymph node metastasis and its effect on the ipsilateral brachial plexus injury. Methods A total of 26 lesions of 22 patients with cervical lymph node metastasis undergoing 125 I seed implantation were retrospectively analyzed. Patients were evaluated for clinical benefit response, 2-month local control, 1-year survival, and complications. Results The follow-up time ranged from 2 to 21 months with a median time of 11 months. The clinical benefit rate was 72.7%, the effective rate was 61.5%, the 2-month local control rate was 84.6%, and the 1-year survival rate was 36.4%. Brachial plexus injury occurred in 4 of these patients. CONCLUSION: The short-term and long-term effect of CT guided irradiation of ~ (125) I seed implantation in patients with cervical lymph node metastasis undergoing continuous internal irradiation is better and the trauma is less. However, the brachial plexus injury is one of the incurable complications Patients with disabilities, seriously affecting the quality of life of patients.