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流行性感冒(简称流感)是一种常见病、多发病,因而流感的预防是极重要的。除了流感减毒活疫苗及灭活疫苗的预防接种外,近年来尚有使用化学药物进行预防。其中以金刚胺及其衍生物较为常用。国内已有金刚胺的生产。现将近年来国外一些资料简要报导如下。金刚胺有预防亚洲甲型流感的效力,但不能治疗其感染。由于金刚胺阻止病毒侵入宿主的细胞而显出其作用,而并不是杀死病毒,对乙型流感无效。通过在志愿者的临床试用和双盲法研究的结果表明:金刚胺对人的亚洲甲型流感有预防作用。剂量:一般每日一次,每次100毫克,连服10～30日。副作用有头痛,眩晕,运动失调,神经过敏,失
Influenza (flu) is a common disease, frequently-occurring disease, and flu prevention is extremely important. In addition to the vaccination of live and attenuated flu attenuated vaccines, chemical drugs have been used for prevention in recent years. Among them amantadine and its derivatives are more commonly used. China has amantadine production. In recent years, some brief reports on foreign materials are as follows. Amantadine has the potential to prevent influenza A in Asia but can not treat it. Since amantadine prevents the virus from invading cells in the host cells, it does not kill the virus and is ineffective against influenza B virus. The results of a clinical trial and double-blind study in volunteers showed that amantadine has a preventive effect on human influenza A in humans. Dosage: General once daily, each 100 mg, and even served 10 to 30 days. Side effects are headache, dizziness, dyskinesia, nervousness, loss