人体通过肝细胞排放入胆汁的物质是依赖各种运输单位完成。胆汁淤积是由于有关胆汁分泌运输蛋白的基因损害或获得性因素引起。胆汁分泌和排泄受很多因素影响 ,如肝细胞水合状态、作用底物、细胞因子、趋化因子、毒素、激素细胞内外调节物和胆汁中各种成分 ,其中对运输蛋白的信 The body discharges into the bile material through the liver cells is dependent on a variety of transport units to complete. Cholestasis is caused by genetic damage or acquired factors related to bile-secreted transport proteins. Bile secretion and excretion are affected by many factors, such as the state of hydration of hepatocytes, substrates of action, cytokines, chemokines, toxins, hormones inside and outside the hormones and bile in various components of which the letter to the transport protein