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目的:分析并研究兰索拉唑联合莫沙必利片治疗反流性食管炎的临床疗效。方法:以2015年本院收治的40例反流性食管炎患者为研究对象,将所有患者随机分为两组,分别为对照组与观察组。选取其中的21例作为观察组,治疗方法为兰索拉唑联合莫沙必利片进行治疗;其余19例为对照组,治疗方法为法莫替丁联合莫沙必利片进行治疗。以8周为周期对两组患者的临床效果、内镜检查结果进行比较。结果:观察组与对照组的临床效果总有效率分别为85.71%,57.90%;观察组与对照组的内镜检查效果总有效率分别为80.95%,63.16%。对比两组数据,具有统计学意义(P<0.05)。结论:相比于法莫替丁联合莫沙必利片治疗反流性食管炎的方法,兰索拉唑联合莫沙必利片的治疗方法更具有临床效果,且效果显著。
Objective: To analyze and study the clinical efficacy of lansoprazole and mosapride in the treatment of reflux esophagitis. Methods: Forty patients with reflux esophagitis admitted to our hospital in 2015 were divided into two groups: control group and observation group. Twenty-one of these patients were selected as the observation group. The treatment was lansoprazole combined with mosapride. The remaining 19 patients were treated with famotidine combined with mosapride. The clinical effects and endoscopic findings of the two groups were compared on a 8-week cycle. Results: The total effective rates of observation group and control group were 85.71% and 57.90% respectively. The total effective rate of endoscopic examination in observation group and control group was 80.95% and 63.16% respectively. Comparing the two groups of data, with statistical significance (P <0.05). Conclusion: Compared with famotidine and mosapride in the treatment of reflux esophagitis, lansoprazole combined with mosapride is more effective and effective.