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孕激素能抑制精子发生,但有性欲减退、阳萎和乳房异常发育等副作用。有人提出在使用孕激素的同时配合使用雄激素可以克服这些缺点。本文在孕激素与雄激素的品种、剂量及用药途径等方面进行了一些研究。作者鉴于17α乙基19去甲睾丸酮的雌激素作用最弱,而且乳房异常发育的副作用最小。据报道每天口服二次每次15毫克,八周后曾造成精子缺乏。因之选用了这一品种作为孕激素部分,但为了减轻副作用,采用了每天20毫克剂量,共口服90天。关于雄激素部分,资料报道曾用睾丸酮皮下埋植三枚,
Progestin can inhibit sperm production, but there are side effects such as loss of libido, impotence and abnormal breast development. It has been suggested that the combination of androgens with progestins can overcome these drawbacks. This article in the progesterone androgen varieties, dosage and route of administration and some other studies. Given the weakest effect of 17α-ethyl-19-nor-testosterone on estrogen and the minimal side-effects of abnormal mammary development. It is reported that oral 15mg twice a day, after eight weeks has caused a lack of sperm. As a result of the selection of this species as part of the progesterone, but in order to reduce side effects, using a daily dose of 20 mg, a total of 90 days orally. About the androgen part, the data reported that three testicles were implanted subcutaneously,