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目的探讨老年难治性原发性高血压患者动态血压与靶器官损害的关系。方法94例老年难治性原发性高血压患者,经动态血压监测分为持续性高血压组(51例)和白大衣效应高血压组(43例),均进行相关的临床、实验室及超声心动图检查,对有关数据进行t检验或χ2检验进行比较。结果持续性高血压组的平均血压、脉压、非勺型动态血压节律、高血压肾病、左心室肥厚等方面均较白大衣效应高血压组明显升高(P<0.05)。结论持续性高血压患者比白大衣效应高血压患者有更多的靶器官损害,需进一步治疗。
Objective To investigate the relationship between ambulatory blood pressure and target organ damage in elderly patients with refractory essential hypertension. Methods Ninety-four elderly patients with refractory essential hypertension were divided into continuous hypertension (51 cases) and white-coat hypertensive (43 cases) by ambulatory blood pressure monitoring. All patients underwent clinical, laboratory and Echocardiography, t-test on the data or χ2 test for comparison. Results The mean blood pressure, pulse pressure, non-dipolar dynamic blood pressure rhythm, hypertensive nephropathy, left ventricular hypertrophy and other aspects of persistent hypertension group were significantly higher than those of white-coat effect hypertensive group (P <0.05). Conclusions Patients with persistent hypertension have more target organ damage than white coat-effect hypertensive patients and need further treatment.