本书由从事药物研究多年,经验较丰富的专家、教授执笔编写。介绍了在药物设计中所涉及的主要基本理论,包括药物的化学结构与生物活性之间的关系,影响药物药效的一些重要因素,以及药物设计的一些基本原理和方法等。全书共分十二章:药物作用机理、药物的吸收分布和排泄、药物的生物转化、理化性质与生物活性、立体化学与生物活性、天然产物与药物设计、前体 Book engaged in drug research for many years, more experienced experts and professors write to write. The main basic theories involved in drug design are introduced, including the relationship between the chemical structure and bioactivity of drugs, some important factors that affect drug efficacy, and some basic principles and methods of drug design. The book is divided into 12 chapters: the mechanism of drug action, drug absorption and distribution and excretion, drug biotransformation, physical and chemical properties and biological activity, stereochemistry and biological activity, natural products and drug design, precursor