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目的:利用放射性核素心室造影技术评价前壁心肌梗死后室壁瘤形成对左心室整体和局部的收缩及舒张功能的影响。材料和方法:患者分为对照组(G0)15名,单纯前壁心肌梗死组(G1)29名,前壁心肌梗死并发室壁瘤组(G2)15名。运用放射性核素心室造影检查技术测定心功能指标:①左室整体收缩功能参数:LVEF、TPE、PER、1/3EF、1/3ER。②左室整体舒张功能参数:TPF、PFR、1/3FF、1/3FR。③左室局部收缩功能参数:LVREF (6个节段)。④左室局部舒张功能参数:LVR1/3FF(6个节段)。结果:①左室整体收缩功能参数,在LVEF、PER、1/3EF、1/3ER中,G2较G1和G0有明显下降(P<0.001)。②左室整体舒张功能参数,PFR、1/3FF、1/3FR,G2比G1和G0有明显下降(P<0.001)。③左室局部收缩功能参数,LVREF在所有1-6节段G2较G1和G0有明显下降(P<0.01)。④左室舒张功能参数,LVR1/3FF在所有1-6节段G2较G1和G0有明显下降(P<0.01)。结论:左心室壁瘤的形成对左心室整体和局部的收缩和舒张功能已经构成了严重的损害。
OBJECTIVE: To evaluate the effects of ventricular aneurysm formation on global and regional left ventricular systolic and diastolic function using radionuclide ventriculography. MATERIALS AND METHODS: The patients were divided into control group (G0) 15, simple anterior wall myocardial infarction group (G1) 29, anterior wall myocardial infarction complicated by aneurysm group (G2) 15. The use of radionuclide ventriculography examination of cardiac function indicators: ① left ventricular systolic function parameters: LVEF, TPE, PER, 1 / 3EF, 1 / 3ER. ② left ventricular diastolic function parameters: TPF, PFR, 1 / 3FF, 1 / 3FR. Left ventricular local systolic function parameters: LVREF (6 segments). Left ventricular local diastolic function parameters: LVR1 / 3FF (6 segments). Results: ① The parameters of left ventricular total systolic function were significantly lower than those of G1 and G0 in LVEF, PER, 1 / 3EF and 1 / 3ER (P <0.001). The left ventricular diastolic function parameters, PFR, 1 / 3FF, 1 / 3FR, G2 were significantly lower than those of G1 and G0 (P <0.001). (3) Left ventricular regional systolic function parameters, LVREF in all 1-6 segments of G2 was significantly lower than G1 and G0 (P <0.01). Left ventricular diastolic function parameters, LVR1 / 3FF in all 1-6 segments G2 compared with G1 and G0 decreased significantly (P <0.01). Conclusion: The formation of left ventricular aneurysm has caused serious damage to global and regional left ventricular systolic and diastolic functions.