组织的修复与再生是复杂动物长寿的必要因素,常依赖干/祖细胞等非特化细胞的增殖。在许多组织中,这些细胞的再生能力随年龄增长而降低,从而导致与衰老相关的许多症状。但是干/祖细胞的增殖是一柄双刃剑,虽然它可确保组织的修复及再生,但亦可能使组织发生过度增殖性疾病,其中最 Tissue repair and regeneration is a necessary factor in the complex animal longevity, often dependent on the proliferation of non-specialized cells such as stem / progenitor cells. In many tissues, the regenerative capacity of these cells decreases with age, leading to many of the symptoms associated with aging. However, the proliferation of stem / progenitor cells is a double-edged sword. Although it can ensure tissue repair and regeneration, it may also cause hyperproliferative diseases in tissues.